Parasite
Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.
Parasite Isoform Specific Products
All Product Categories
-
Parasite Related Products (2504)
Related Products (2504)
-
Related Compound Screening Libraries (1)
-
Parasite Isoform Comparison
-
Ibuprofen-13C,d3
0 ImagesCat. No.: HY-78131S1CAS No.: 1261394-40-4Synonyms: (±)-Ibuprofen-13C,d3
-
7-Acetoxybonducellpin C
0 ImagesCat. No.: HY-N2753CAS No.: 197781-86-57-Acetoxybonducellpin C, a diterpenoid, is a nature product that could be isolated from the seed kernels of Caesalpinia crista. 7-Acetoxybonducellpin C has antimalarial activity.
-
Lychnopholide
0 ImagesCat. No.: HY-129228CAS No.: 77448-64-7Lychnopholide is a sesquiterpene lactone derived from the Asteraceae, Lychnopholide exhibits anti-trypanosomal activity against Trypanosoma cruzi. lychnopholide encapsulated in nanocapsules reduces its toxicity to mammalian cells. Lychnopholide ameliorates Chagas disease in mouse models.
-
4,6-Dibromo indole
0 ImagesCat. No.: HY-W102893CAS No.: 99910-50-64,6-Dibromo indole is a natural product found in the adipose tissue of bottlenose dolphins, algae, and invertebrates including species of the genus Tubastrea, with multiple activities such as nematicidal and antifungal properties. 4,6-Dibromo indole inhibits the motility of Caenorhabditis elegans and induces a multi-stage nematicidal effect. 4,6-Dibromo indole inhibits the growth, biofilm formation, and yeast-hypha transition of Candida, induces ROS accumulation, disrupts hyphal networks, and reduces biofilm biomass. 4,6-Dibromo indole can be used in studies on crop damage related to nematode infestation and Candida infection.
-
Imidocarb dihydrochloride monohydrate
0 ImagesCat. No.: HY-135611AImidocarb dihydrochloride monohydrate is a potent antiprotozoal agent. Imidocarb dihydrochloride monohydrate is active against the parasite B. bovis with an IC50 of 87 μg/mL.
-
Tizoxanide (Standard)
0 ImagesCat. No.: HY-12687RCAS No.: 173903-47-4Synonyms: TIZ (Standard)Tizoxanide (Standard) is the analytical standard of Tizoxanide. This product is intended for research and analytical applications. Tizoxanide (TIZ) is the active metabolite of Nitazoxanide, which is a thiazolide anti-infective compound against anaerobic bacteria, protozoa, and a range of viruses. Tizoxanide (TIZ) has anti-HIV-1 activities and potent inhibition of both HBV and HCV replication with values EC50 of 0.46μM and 0.15 μM, respectively. Tizoxanide also exerts anti-inflammatory effects by inhibiting the production of pro-inflammatory cytokines and suppressing of the activation of the NF-κB and the MAPK signaling pathways in LPS-treated macrophage cells.
-
Argifin (Standard)
0 ImagesCat. No.: HY-P2274RCAS No.: 243975-37-3Argifin (Standard) is the analytical standard of Argifin. This product is intended for research and analytical applications. Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC50s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively[1].
-
Narasin sodium
0 ImagesCat. No.: HY-112225CAS No.: 58331-17-2Narasin sodium is a cationic ionophore and coccidiostat agent. Narasin inhibits NF-κB signaling and induces tumor cells apoptosis. Narasin sodium has antimicrobial and anticancer activity.
-
AcrB-IN-3
0 ImagesCat. No.: HY-149811CAS No.: 2890177-94-1Efflux pump-IN-3 is an AcrB efflux pump inhibitor, with ability to potentiate the effect of antibiotics. Efflux pump-IN-3 inhibits Nile Red (a known substrate of AcrB) efflux. Efflux pump-IN-3 does not disrupts the bacterial outer membrane nor display toxicity in a nematode model.
-
Luxabendazole
0 ImagesCat. No.: HY-122765CAS No.: 90509-02-7Synonyms: HOE 216VLuxabendazole (HOE 216V) is an effective anthelmintic against trematodes, cestodes and nematodes.
-
Purine phosphoribosyltransferase-IN-2
0 ImagesCat. No.: HY-144296CAS No.: 2784631-30-5Purine phosphoribosyltransferase-IN-2 is a potent inhibitor of the Plasmodium falciparum ((Pf)), Plasmodium vivax ((Pv)) and Trypanosoma brucei ((Tbr)) 6-oxopurine phosphoribosyltransferase (PRT), with Kis of 30, 20 and 2 nM, respectively.
-
Secnidazole-13C2, 15N2
0 ImagesCat. No.: HY-B1118S1Synonyms: RP-14539-13C2, 15N2; PM-185184-13C2, 15N2Secnidazole-13C2, 15N2 is the 13C2, 15N2 labeled Secnidazole. Secnidazole (RP-14539;PM-185184) is an orally active azole antibiotic with a longer half-life than metronidazole (HY-B0318). Secnidazole is against the vaginosis-associated bacteria and has the potential for bacterial vaginosis research.
-
UA2239
0 ImagesCat. No.: HY-179656CAS No.: 2455422-89-4UA2239 is an antimalarial agent and acyclic nucleoside phosphonate. UA2239 disrupts the essential cGMP-dependent egress pathway by decreasing cGMP levels. UA2239 targets guanylyl cyclase α. UA2239 demonstrates rapid and irreversible inhibitory effects on Plasmodium parasites.
-
Antimalarial agent 37
0 ImagesCat. No.: HY-161171CAS No.: 2982633-16-7Antimalarial agent 37 (compound 33) is a selective inhibitor against Type Ⅱ kinase with antiplasmodial activity. Antimalarial agent 37 exhibited cytotoxicity and selectivity towards cancer cells HepG2 and MCF 7.
-
Toltrazuril sulfoxide (Standard)
0 ImagesCat. No.: HY-136438RCAS No.: 69004-15-5Toltrazuril sulfoxide (Standard) is the analytical standard of Toltrazuril sulfoxide. This product is intended for research and analytical applications. Toltrazuril sulfoxide is a short-lived intermediary metabolite of Toltrazuril (HY-B0175), and then can be metabolized to the reactive toltrazuril sulfone (TZR-SO2) in vivo. Toltrazuril is an antiprotozoal agent that acts upon Coccidia parasites.
-
Antitrypanosomal agent 10
0 ImagesCat. No.: HY-151942Antitrypanosomal agent 10 is an antitrypanosomal agent that inhibits Trypanosoma cruzi with an IC50 of 0.28 μM.
-
SKF-83566 hydrochloride
0 ImagesCat. No.: HY-103430BCAS No.: 164265-49-0SKF-83566 hydrochloride is an orally active, blood-brain barrier-permeable D1/D5 dopamine receptor antagonist with a Ki value of approximately 0.4-0.56 nM. SKF-83566 hydrochloride modulates locomotor behavior and spatial memory by blocking D1 receptors and inhibits glioblastoma progression by targeting the DRD1/c-Myc/UHRF1 pathway. SKF-83566 hydrochloride acts as an inhibitor of the dopamine transporter (DAT) and adenylyl cyclase 2 (AC2). SKF-83566 hydrochloride competitively binds to DAT to inhibit dopamine reuptake and non-competitively inhibits AC2 activity, thereby reducing cAMP accumulation. SKF-83566 hydrochloride is used in research areas such as dopaminergic system mechanisms, learning and memory, targeted intervention for glioblastoma, AC2 pathophysiology, antiparasitic drug screening, and synaptic plasticity (the "gating effect").
